Secretariat, Alumni Association, IDAC
Date	Monday, 7 July 2025, 14:00～16:00.
Room	International Conference Room, Center for Smart-Aging Research,1F, (IDAC)
Title	Emerging biomarkers for vascular cognitive impairment
Speaker	Jason Hinman
Affiliation	Alzheimer’s Disease Program Director Department of Neurology University of California Los Angeles
Abstract	Cerebral small vessel disease is a common, progressive endotheliopathy and a major driver of cognitive impairment and dementia. These vascular contributions to cognitive impairment and dementia (VCID) develop in parallel with traditional pathologies associated with Alzheimer’s disease, necessitating reproducible biomarkers that characterize the presence and progression of VCID. This talk will summarize emerging imaging and fluid biomarkers for VCID.
Title	Accelerating Neurovascular Device Innovation From Bench to Bedside
Speaker	Naoki Kaneko, M.D., Ph.D.
Affiliation	Division of Interventional Neuroradiology, Ronald Reagan UCLA Medical Center
Abstract	This seminar explores the development of medical devices in the neurovascular field, highlighting a cyclical research process bridging fundamental scientific inquiry and clinical practice. Serving as a principal investigator and attending physician in the US, the presenter has consistently focused on translating clinical questions into laboratory explorations, subsequently integrating findings back into patient care. Since 2013, my research team has utilized advanced 3D printing technologies to create detailed physical models representing intracranial vessels and various vascular conditions, including cerebral aneurysms, stenosis, thrombus retrieval scenarios, and cerebral arteriovenous malformations. These sophisticated models have significantly accelerated the refinement and evaluation of traditional endovascular techniques and the development of novel devices. The ongoing iterative relationship between bench research and clinical application underscores a dynamic, symbiotic interplay, facilitating rapid translation of laboratory discoveries into enhanced clinical practices and patient outcomes. This presentation provides an in-depth overview of these transformative activities, from basic scientific research to innovative clinical device development.
Organizer	Yasuyuki Taki（Dept.of Aging Research and Geriatric Medicine・ext8559） Taizen Nakase (Dept.of Aging Research and Geriatric Medicine・ext8559）