|Senior Assistant Professor||Ryutaro SHIRAKAWA|
The Department of Molecular and Cellular Biology investigates intracellular signals focusing on small GTPases, and by utilizing biochemical methods, we have identified several important signaling molecules implicated in several functions such as exoxytosis and oncogenesity. Particularly, we are focusing on the physiological and pathological functional importance of RalGAP that we earlier discovered.
•Biochemical and cell-biological analysis of intracellular signaling factors.
•Analysis of vascular formation, hemostasis and thrombosis using gene-knockout mice.
•Analysis of metabolic syndrome using gene-knockout mice.
•Identification of novel cancer-related genes.
•Development of anti-cancer drugs.