Secretariat, Alumni Association, IDAC
Date Monday, 17 December 2018, 16:00~
Room Center for Smart Aging Research 1F, IDAC
Title Preclinical functional imaging of rodents for translational study
Speaker Tomokazu Tsurugizawa
Affiliation NeuroSpin/CEA-Saclay, Gif-sur-Yvette, France
Organizer Rie Ryoke (Dept. of Advanced Brain Science・ext 8466)
Abstract Functional MRI (fMRI) is a promising noninvasive tool to investigate neuronal activity by catching changes in the circumstances around the proton (neurovascular coupling, chemical shift and so forth). This technique has been used in clinical studies in a wide field from neuroscience to medical science. Recently, the development of high field MRI provides high resolution and high contrast functional imaging of the rodent brain. Therefore, fMRI is expected for bidirectional translational study between rodent and humans. However, there is still a gap between animal basic research and fMRI research. In this seminar, I will introduce the advantages and limitations of rodent fMRI in addition to recent combination studies of MRI and other neuroscience methods (disease model animals, chemogenetics, electrophysiology and so forth). As this seminar aims to discuss rodent fMRI for translational study, researchers outside the MRI field as well as MRI researchers are welcome to join.