|Professor||Toshiyuki TAKAI, PhD|
|Senior Assistant Professor||Masanori INUI, PhD|
|Guest Instructor||Akira NAKAMURA, MD, PhD (Tohoku Medical and Pharmaceutical University)|
|Guest Instructor||Motoko MORIMOTO, DVM, PhD (Miyagi University)|
|Guest Instructor||Yuzuru SAKAMOTO, PhD (Tohoku Gakuin University)|
|Assistant Professor||Ari ITOH-NAKADAI, PhD|
|Technical Assistant||Akiko TOBINAI|
|Secretarial Assistant||Takako NAKAMURA|
The Department of Experimental Immunology focuses on Immunoregulation by Immunoglobulin-Like Receptors (IgLRs). We are developing the research for overcoming immune diseases through the investigation of physiological roles of inhibitory receptors, such as FcγRIIB and PIR-B.
•Regulatory mechanisms of immune cell development and autoantibody production by immunoreceptor signaling.
•Functional network of immunoregulatory receptors expressed on B-cells and their dynamics on the cell surface and in the intracellular compartments.
•Modulation of effector T-cells participating in transplantation and tumor immunity through enhancement of regulatory receptor-mediated functions.
•Development of animal models for allergy and autoimmune diseases and their utilization for delineation of novel therapeutic tools and procedures.
•Evaluation techniques of disease susceptibilities by bio-informatics profiling of natural antibodies in sera.