Institute of Development, Aging and Cancer, Tohoku University

Research

Research Area

Mechanism of aging

遺伝子発現制御分野 Dept. Gene Expression Regulation
Professor:Hozumi Motohashi
E-mail: hozumim@idac.
Phone: 022-717-8550
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Research Topics
  • Transcriptional regulation for metabolic reprogramming and stress response in cancer cells
  • Intranuclear redox balance and genome protection in carcinogenesis
  • Stress response and epigenetic memory of hematopoietic stem cells in chronic inflammation
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    遺伝子導入研究分野 Dept. Experimental Immunology
    Professor:Toshiyuki Takai
    E-mail: tostakai@idac.
    Phone: 022-717-8501
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    Research Topics
  • Regulatory mechanisms of immune cell development and autoantibody production by immunoreceptor signaling
  • Functional network of immunoregulatory receptors expressed on B cells and their dynamics on the cell surface and in the intracellular compartments
  • Modulation of effector T cells participating in transplantation and tumor immunity through enhancement of regulatory receptor-mediated functions
  • Development of animal models for allergy and autoimmune diseases and their utilization for delineation of novel therapeutic tools and procedures
  • Evaluation techniques of disease susceptibilities by bio-informatics profiling of natural antibodies in sera
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    生体防御学分野 Dept. Immunobiology
    Professor:Kouetsu Ogasawara
    E-mail: imbio1@idac.
    Phone: 022-717-8579
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    Research Topics
  • Metal Allergy
  • Infection and Immunity
  • Tumor Immunology
  • Autoimmune diseases
  • Immune cell recognition against target cells
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    基礎加齢研究分野 Dept. Molecular and Cellular Biology
    Professor:Hisanori Horiuchi
    E-mail: horiuchi@idac.
    Phone: 022-717-8463
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    Research Topics
  • Biochemical and cell-biological analysis of intracellular signaling factors
  • Analysis of vascular formation, hemostasis and thrombosis using gene-knockout mice
  • Analysis of metabolic syndrome using gene-knockout mice
  • Indentificatin of novel cancer-related genes
  • Development of anti-cancer drugs

  • 代謝制御分野 Dept. Metabolism
    Professor:Tokuo YAMAMOTO
    E-mail: grc@idac.
    Phone: 022-717-8875
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    Research Topics
  • Metabolic regulation of cholesterol and lipid metabolism
  • Metabolic regulation of glucose and carbohydrate
  • Functional genomics of diabetes
  • Metabolic regulation of genes
  • Functional analysis of genes

  • 心臓病電子医学分野 Dept. Medical Engineering and Cardiology
    Professor:Tomoyuki YAMBE
    E-mail: yambe@idac.
    Phone: 022-717-8517
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    Research Topics
  • Artificial heart development
  • clinical research in Cardiology
  • Ventricular assist device development and implantation
  • Artificial esophagus, whicn can drink
  • Artificial sphincter
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    イン•シリコ解析研究分野 Dept. In Silico
    Professor:Kengo KINOSHITA
    E-mail:kengo@ecei.
    Phone:022-795-7179
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    Research Topics
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      Dept. Project Programs
    Professor:Masanobu SATAKE
    E-mail: satake@idac.
    Phone: 022-717-8477
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    抗感染症薬開発寄附研究部門 Div. Anti-Infective Agents
    Professor:Akira WATANABE
    E-mail: akiwa@idac.
    Phone: 022-717-8540
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    Research Topics
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    加齢ゲノム制御 プロテオーム寄附研究部門 Div. Dynamic Proteome in Aging and Cancer
    Professor:Akira YASUI
    E-mail:ayasui@idac.
    Phone:
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    Research Topics
  • DNA repair in cancer, cancer therapy, aging and evolution
  • DNA repair mechanisms in living human cell
  • Chromatin remodeling in response to DNA damage and aging
  • Cancer therapy by use of DNA repair deficiency of cancer cell
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    附属医用細胞資源センター Cell Resource Center for Biomedical Research
    Professor:Yasuhisa Matsui
    E-mail: ymatsui@idac.
    Phone: 022-717-8571
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    Research Topics
  • Identification and functional analysis of genes involved in germ cell formation and their differentiation
  • Epigenomic analysis in germ cells
  • Molecular mecchanisms regulating conversion between germ cells and pluripotential stem cells
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